Deletion of PTP1B in cardiomyocytes alters cardiac metabolic signaling to protect against cardiomyopathy induced by a high-fat diet

By afschroeder • July 24, 2025

Sun Y, Mishra AK, Chanrasekhar V, Door M, Kessinger CW, Xu B, Tang P, Gao Y, Kamli-Salino S, Nelson K, Delibegovic M, Abel ED, Kirk JA, Kontaridis MI. Deletion of PTP1B in cardiomyocytes alters cardiac metabolic signaling to protect against cardiomyopathy induced by a high-fat diet. Sci Signal. 2025 Jul 22;18(896):eadp6006. doi: 10.1126/scisignal.adp6006. Epub 2025 Jul 22. PMID: 40694612.

Tags: Endocrinology, Publications

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