Modulation of the PTPRS proteoglycan switch by antibodies binding to the membrane-proximal fibronectin-type III domain

By afschroeder • July 13, 2025

Hein Da Rosa T, Ramsey SH, Lee JJ, Kozlova NY, Zhao Z, Kim J, Schneider AC, Li S, Katiki M, Firestein GS, Murali R, Santelli E, Stanford SM, Bottini N. Modulation of the PTPRS proteoglycan switch by antibodies binding to the membrane-proximal fibronectin-type III domain. J Biol Chem. 2025 Jul 10:110470. doi: 10.1016/j.jbc.2025.110470. Epub ahead of print. PMID: 40651610.

Tags: antibody, Cedars Sinai DoM, phosphatase, proteoglycan, Publications, receptor regulation, Rheumatology

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