Polyfunctional T follicular helper cells drive checkpoint-inhibitor diabetes and are targeted by JAK inhibitor therapy

By afschroeder • July 9, 2025

Huang NL, Ortega JG, Kimbrell K, Lee J, Scott LN, Peluso EM, Wang SJ, Kao EY, Kim K, Olay J, Nguyen JN, Quandt Z, Angell TE, Su MA, Lechner MG. Polyfunctional T follicular helper cells drive checkpoint-inhibitor diabetes and are targeted by JAK inhibitor therapy. JCI Insight. 2025 Jul 8;10(13):e188843. doi: 10.1172/jci.insight.188843. PMID: 40626363.

Tags: Autoimmune Diseases, autoimmunity, cancer immunotherapy, diabetes, Endocrinology, oncology, Publications

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