Novel and superior treatment of pulmonary hypertension with netrin-1 derived, modified and improved small peptides

By sjmartinez • July 1, 2025

Murugesan P, Zhang Y, Zhang Y, Youn JY, Cai H. Novel and superior treatment of pulmonary hypertension with netrin-1 derived, modified and improved small peptides. Redox Biol. 2025 Jun 13;85:103710. doi: 10.1016/j.redox.2025.103710. Epub ahead of print. PMID: 40580754.

Tags: Cardiology/Epi, Endothelial nitric oxide synthase uncoupling, eNOS, hypoxia, Mitochondrial superoxide production, Netrin-1, Netrin-1 derived small peptides, NO bioavailability, Publications, pulmonary hypertension, Pulmonary vascular remodeling, reactive oxygen species, Right ventricular hypertrophy, ROS, Translational

Engineering an in vivo charging station for CAR-redirected invariant natural killer T cells to enhance cancer therapy

Li YR, Nan H, Liu Z, Fang Y, Zhu Y, Lyu Z, Shao Z, Zhu E, Zhang B, Yang Y, Shen X, Chen Y, Hsiai[...]

Pharmacologic Management of Ventricular Arrhythmias: Targeting Nicotinic Signaling Mechanisms

Ahluwalia N, Hanna P, Shivkumar K. Pharmacologic Management of Ventricular Arrhythmias: Targeting Nicotinic Signaling Mechanisms. J Am Coll Cardiol. 2026 Mar 10:S0735-1097(26)05234-4. doi: 10.1016/j.jacc.2026.01.084. Epub[...]

Echocardiography in HIV Disease

Durstenfeld MS, Kizer JR. Echocardiography in HIV Disease. Curr Cardiol Rep. 2026 Mar 18;28(1):34. doi: 10.1007/s11886-026-02353-9. PMID: 41848979.