Novel and superior treatment of pulmonary hypertension with netrin-1 derived, modified and improved small peptides

By sjmartinez • July 1, 2025

Murugesan P, Zhang Y, Zhang Y, Youn JY, Cai H. Novel and superior treatment of pulmonary hypertension with netrin-1 derived, modified and improved small peptides. Redox Biol. 2025 Jun 13;85:103710. doi: 10.1016/j.redox.2025.103710. Epub ahead of print. PMID: 40580754.

Tags: Cardiology/Epi, Endothelial nitric oxide synthase uncoupling, eNOS, hypoxia, Mitochondrial superoxide production, Netrin-1, Netrin-1 derived small peptides, NO bioavailability, Publications, pulmonary hypertension, Pulmonary vascular remodeling, reactive oxygen species, Right ventricular hypertrophy, ROS, Translational

Related Posts

Large-bore mechanical thrombectomy vs standard of care for acute high-risk pulmonary embolism: rationale and design of the PERSEVERE randomized controlled trial

Chopard R, Hobohm L, Barco S, Bangalore S, Giri J, Mahfoud F, Moriarty J, Rosenkranz S, Sharp A, Thiele H, Toma C, Tapson VF, Markovitz[...]

Trends and Projections in Hypertension-Related Mortality in the United States: A 1979-2050 CDC WONDER Analysis

Ahmed M, Abbas F, Khan S, Qureshi S, Khan GT, Shafiq SB, Imran W, Waqas SA, Fudim M, Fonarow GC, Greene SJ, Khan MS. Trends[...]

Xu H, Grory BCM, Ikeaba U, Alhanti B, Fonarow GC, Schwamm LH, Smith EE, Messe SR, Ostbye T, De Lemos JA, Peterson ED, Xian Y.[...]