Adding Intranasal to Oral Administration of an Ultra-rapid Near Universal Drug Regimen Accelerates Relapse-free Cure of Tuberculosis in Mice

By afschroeder • June 12, 2025

Lee BY, Clemens DL, Masleša-Galic S, Nava S, Lo CY, Zink JI, Horwitz MA. Adding Intranasal to Oral Administration of an Ultra-rapid Near Universal Drug Regimen Accelerates Relapse-free Cure of Tuberculosis in Mice. J Infect Dis. 2025 Jun 11:jiaf315. doi: 10.1093/infdis/jiaf315. Epub ahead of print. PMID: 40498595.

Tags: bedaquiline, delamanid, Infectious Diseases, intranasal therapy, Mycobacterium tuberculosis, Parabolic Response Surface, PRS Regimen V, Publications, relapse-free cure, Tuberculosis

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