Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1

By sjmartinez • May 29, 2025

Xue J, Zeng W, John S, Attiq N, Ottolia M, Jiang Y. Structural mechanisms of PIP₂activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1. Elife. 2025 May 28;14:RP105396. doi: 10.7554/eLife.105396. PMID: 40433952; PMCID: PMC12119087.

Tags: cardiac sodium-calcium exchanger, Cardiology/Epi, human, molecular biophysics, PIP2 activation, Publications, SEA0400 inhibition, structural biology

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