rLVS(delta) capB/Yp F1-V single vector platform vaccine expressing Yersinia pestis F1 and LcrV antigens provides complete protection against lethal respiratory challenge with virulent plague bacilli

By sjmartinez • May 27, 2025

Jia Q, Bowen RA, Masleša-Galić S, Horwitz MA. rLVS ΔcapB/Yp F1-V single vector platform vaccine expressing Yersinia pestis F1 and LcrV antigens provides complete protection against lethal respiratory challenge with virulent plague bacilli. Hum Vaccin Immunother. 2025 Dec;21(1):2507475. doi: 10.1080/21645515.2025.2507475. Epub 2025 May 26. PMID: 40417828.

Tags: bioterrorism, F1, Francisella tularensis, Infectious Diseases, LcrV, LVS ΔcapB, plague, Publications, single vector platform vaccine, Tier 1 select agent, vaccine, Yersinia pestis

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