Macitentan and Tadalafil Combination Therapy in Patients with Pulmonary Arterial Hypertension and Cardiovascular Comorbidities: Real-World Evidence from OPUS and OrPHeUS

By sjmartinez • May 20, 2025

Kim NH, Chin KM, McLaughlin VV, Ong R, MacDonald G, Martin N, Senatore A, Channick R. Macitentan and Tadalafil Combination Therapy in Patients with Pulmonary Arterial Hypertension and Cardiovascular Comorbidities: Real-World Evidence from OPUS and OrPHeUS. Adv Ther. 2025 May 19. doi: 10.1007/s12325-025-03180-0. Epub ahead of print. PMID: 40388087.

Tags: Cardiovascular comorbidities, combination therapy, Hospitalization, Macitentan, Publications, pulmonary arterial hypertension, Pulmonary, Critical Care & Sleep Medicine, real-world data, safety, survival, Tadalafil

Real-World Effectiveness and Safety of Evinacumab in Children and Adults With Homozygous Familial Hypercholesterolemia: A Multisite US Perspective

Wilkinson MJ, Bijlani P, Davidson MH, Duell PB, Horan M, Malloy MJ, Newfield RS, Pradeep P, Shah PK, Stock EO, Warden BA, Ito MK. Real-World[...]

Eosinophilic Granulomatosis With Polyangiitis Presenting as Bilateral Orbital Inflammation

Zhu L, Dahhan T. Eosinophilic Granulomatosis With Polyangiitis Presenting as Bilateral Orbital Inflammation. Cureus. 2025 Apr 28;17(4):e83131. doi: 10.7759/cureus.83131. PMID: 40438859; PMCID: PMC12118515.

Methylation risk score of C-reactive protein associates sleep health with related health outcomes

Wang Z, Wallace DA, Spitzer BW, Huang T, Taylor KD, Rotter JI, Rich SS, Liu PY, Daviglus ML, Hou L, Ramos AR, Kaur S, Durda[...]