Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males

By sjmartinez • May 7, 2025

Zhou Z, Moore TM, Strumwasser AR, Ribas V, Iwasaki H, Morrow N, Ma A, Tran PH, Wanagat J, de Aguiar Vallim TQ, Clifford B, Zhang Z, Sallam T, Parks BW, Reue K, Shirihai O, Acin-Perez R, Morselli M, Pellegrini M, Mahata SK, Norheim F, Zhou M, Seldin MM, Lusis AJ, Lee CC, Goodarzi MO, Rotter JI, Hansen JR, Drucker B, Sagendorf TJ, Adkins JN, Sanford JA, DeMayo FJ, Hewitt SC, Korach KS, Hevener AL. Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males. Cell Rep Med. 2025 May 2:102116. doi: 10.1016/j.xcrm.2025.102116. Epub ahead of print. PMID: 40328250.

Tags: Cardiology/Epi, Dermatology, Endocrinology, estrogen action, exercise adaptation, Geriatrics, insulin sensitivity, mitochondrial cristae architecture, mitochondrial function, mtDNA replication, oxidative metabolism, Publications, Veterans Administration

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