Predicting Maternal and Fetal Exposures of Elexacaftor-Tezacaftor-Ivacaftor during Pregnancy through Physiologically Based Pharmacokinetic Models

Hong E, Hebert MF, Fay E, Turner G, Eshaghian P, Trimble A, Chung PS, Rao AP, Beringer PM. Predicting Maternal and Fetal Exposures of Elexacaftor-Tezacaftor-Ivacaftor during Pregnancy through Physiologically Based Pharmacokinetic Models. Clin Pharmacol Ther. 2025 May 5. doi: 10.1002/cpt.3705. Epub ahead of print. PMID: 40323155.


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