Predicting Maternal and Fetal Exposures of Elexacaftor-Tezacaftor-Ivacaftor during Pregnancy through Physiologically Based Pharmacokinetic Models

By sjmartinez • May 6, 2025

Hong E, Hebert MF, Fay E, Turner G, Eshaghian P, Trimble A, Chung PS, Rao AP, Beringer PM. Predicting Maternal and Fetal Exposures of Elexacaftor-Tezacaftor-Ivacaftor during Pregnancy through Physiologically Based Pharmacokinetic Models. Clin Pharmacol Ther. 2025 May 5. doi: 10.1002/cpt.3705. Epub ahead of print. PMID: 40323155.

Tags: Publications, Pulmonary, Critical Care & Sleep Medicine

Prognostic communication, psychological distress, and caregiving burden among caregivers of patients with decompensated cirrhosis

Li L, Donlan J, Nurhussien L, Horick N, Zeng C, Indriolo T, Armstrong ME, Bizup G, Dalvi A, Zhu E, Diop MS, Mason N, Engel[...]

Amara Yad Image: The Relationship of the Pulmonary Artery to the Atrio-Caval Junction

Shivkumar K. Amara Yad Image: The Relationship of the Pulmonary Artery to the Atrio-Caval Junction. J Am Coll Cardiol. 2025 Oct 28;86(17):1456-1458. doi: 10.1016/j.jacc.2025.09.026. Epub[...]

Considerations for Endpoints in Lung Transplant Clinical Trials: An ISHLT Consensus Statement

Greenland JR, Perch M, Halloran K, Levine DJ, Morrell ED, Reed A, Shaver CM, Singer JP, Sweet SC, Vos R, Aryal S, Avdimiretz N, Burrows[...]