PPARα regulates ER-lipid droplet protein Calsyntenin-3β to promote ketogenesis in hepatocytes

By sjmartinez • April 22, 2025

Uchiyama LF, Nguyen A, Qian K, Cui L, Pham KT, Xiao X, Gao Y, Shimanaka Y, Tol MJ, Vergnes L, Reue K, Tontonoz P. PPARα regulates ER-lipid droplet protein Calsyntenin-3β to promote ketogenesis in hepatocytes. Proc Natl Acad Sci U S A. 2025 Apr 29;122(17):e2426338122. doi: 10.1073/pnas.2426338122. Epub 2025 Apr 21. PMID: 40258152.

Tags: Digestive Diseases, hepatocyte, ketogenesis, ketogenic diet, lipid metabolism, Publications

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