Noninvasive Assessment of β-Secretase Activity Through Click Chemistry-Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer’s Disease

By sjmartinez • April 18, 2025

Kim H, Lee J, Qian A, Ji YR, Zhang R, Hu Q, Williams CK, Chuang HY, Smalley MD, Xu Y, Gao L, Mayo MC, Zhang T, Posadas EM, Tan ZS, Vinters HV, Vossel K, Magaki S, Zhu Y, Tseng HR. Noninvasive Assessment of β-Secretase Activity Through Click Chemistry-Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease. Adv Sci (Weinh). 2025 Apr 17:e2415289. doi: 10.1002/advs.202415289. Epub ahead of print. PMID: 40245252.

Tags: Alzheimer’s disease, Cedars Sinai DoM, General Internal Medicine, Hematology/Oncology, Liquid biopsy, neurodegenerative disease, neuronal extracellular vesicle, Publications, β‐secretase

Elacestrant in Combination with Everolimus for Estrogen Receptor-Positive, HER2-Negative Previously Treated Advanced Breast Cancer: Results from ELEVATE

Rugo HS, Tolaney SM, Chan N, Borges G, Yerushalmi R, Sharifi MN, McHayleh W, Beck T, Vidula N, Hamilton E, Rinn KJ, O'Shaughnessy J, Curigliano[...]

Insights on supplement use during cancer care from online Reddit conversations

Waissengrin B, O'Connor K, Shirazipour CH, Ivan FA, Reckamp KL, Gonzalez-Hernandez G, Figueiredo JC. Insights on supplement use during cancer care from online Reddit conversations.[...]

South Asian Cardiovascular Risk: Role of Coronary Artery Calcium Scoring and Computed Tomography Angiography

Kalra DK, Vedamurthy D, Hosadurg N, Goyal A, Gupta M, Pagidipati N, Slipczuk L, Dey D, Mehta A, Joshi P, Baskaran L, Wong N, Virani[...]