Noninvasive Assessment of β-Secretase Activity Through Click Chemistry-Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer’s Disease

By sjmartinez • April 18, 2025

Kim H, Lee J, Qian A, Ji YR, Zhang R, Hu Q, Williams CK, Chuang HY, Smalley MD, Xu Y, Gao L, Mayo MC, Zhang T, Posadas EM, Tan ZS, Vinters HV, Vossel K, Magaki S, Zhu Y, Tseng HR. Noninvasive Assessment of β-Secretase Activity Through Click Chemistry-Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease. Adv Sci (Weinh). 2025 Apr 17:e2415289. doi: 10.1002/advs.202415289. Epub ahead of print. PMID: 40245252.

Tags: Alzheimer’s disease, Cedars Sinai DoM, General Internal Medicine, Hematology/Oncology, Liquid biopsy, neurodegenerative disease, neuronal extracellular vesicle, Publications, β‐secretase

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