The Spatial Transcriptional Activity of Hepatic TCF7L2 Regulates Zonated Metabolic Pathways that Contribute to Liver Fibrosis

By sjmartinez • April 11, 2025

Ayala I, Hebbale SK, Mononen J, Brearley-Sholto MC, Shannon CE, Valdez I, Fourcaudot M, Bakewell TM, Zagorska A, Romero G, Asmis M, Musa FA, Sily JT, Smelter AA, Hinostroza EA, Freitas Lima LC, de Aguiar Vallim TQ, Heikkinen S, Norton L. The Spatial Transcriptional Activity of Hepatic TCF7L2 Regulates Zonated Metabolic Pathways that Contribute to Liver Fibrosis. Nat Commun. 2025 Apr 10;16(1):3408. doi: 10.1038/s41467-025-58714-5. PMID: 40210847.

Tags: Cardiology/Epi, Post Doc, Publications

Association Between Colchicine Use and Clinical Outcomes Post Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials

Jaiswal V, Hanif M, Raja HAA, Khadka S, Deb N, Mashkoor Y, Ahmed A, Rajak K, Jaiswal AK, Gupta M, Hirji S, Fonarow GC, Qamar[...]

A Multicenter Randomized Controlled Trial of a Digital Health Intervention for Medication Optimization in Heart Failure: The ENGAGE-HF Trial Outcomes

Dorsch MP, Gilotra NA, Spaulding EM, Martin SS, Zhao H, Wilson GA, Poddar M, Verma A, Schmiedmayer P, Kraft P, Rodriguez F, Azizi Z, Hwang[...]

Digital Health Intervention to Optimize Heart Failure Management After Hospital Discharge in Brazil (OPT-HF): A Randomized Clinical Trial

Ciminelli ALA, Sandhu AT, Longenecker CT, Rezende LC, Camelo LV, Gonçalves BPA, Lino RZS, Bramucci V, Melo BMH, Siqueira CV, Carvalho APV, Ribeiro EG, Ferreira[...]