Observational, causal relationship and shared genetic basis between cholelithiasis and gastroesophageal reflux disease: evidence from a cohort study and comprehensive genetic analysis

By sjmartinez • March 28, 2025

Lyu Y, Tong S, Huang W, Ma Y, Zeng R, Jiang R, Luo R, Leung FW, Lian Q, Sha W, Chen H. Observational, causal relationship and shared genetic basis between cholelithiasis and gastroesophageal reflux disease: evidence from a cohort study and comprehensive genetic analysis. Gigascience. 2025 Jan 6;14:giaf023. doi: 10.1093/gigascience/giaf023. PMID: 40139907; PMCID: PMC11943489.

Tags: causal association, cholelithiasis, Cohort study, Digestive Diseases, gastroesophageal reflux disease, genetic analyses, Mendelian randomization, Publications, shared genetic basis, Veterans Administration

Expanding the menu of dietary therapies in irritable bowel syndrome

Shin A. Expanding the menu of dietary therapies in irritable bowel syndrome. Lancet Gastroenterol Hepatol. 2025 Apr 18:S2468-1253(25)00070-6. doi: 10.1016/S2468-1253(25)00070-6. Epub ahead of print. PMID:[...]

PPARα regulates ER-lipid droplet protein Calsyntenin-3β to promote ketogenesis in hepatocytes

Uchiyama LF, Nguyen A, Qian K, Cui L, Pham KT, Xiao X, Gao Y, Shimanaka Y, Tol MJ, Vergnes L, Reue K, Tontonoz P. PPARα[...]

Differential brainstem connectivity according to sex and menopausal status in healthy male and female individuals

Kilpatrick LA, Church A, Meriwether D, Mahurkar-Joshi S, Li VW, Sohn J, Reist J, Labus JS, Dong T, Jacobs JP, Naliboff BD, Chang L, Mayer[...]