ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase

By sjmartinez • March 21, 2025

Kumari A, Larsen SWR, Bondesen S, Qian Y, Tian HD, Walker SG, Davies BSJ, Remaley AT, Young SG, Konrad RJ, Jørgensen TJD, Ploug M. ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase. Proc Natl Acad Sci U S A. 2025 Mar 25;122(12):e2420721122. doi: 10.1073/pnas.2420721122. Epub 2025 Mar 20. PMID: 40112106.

Tags: Cardiology/Epi, lipase, lipolysis, Publications, triglycerides

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