Mitochondrial reactive oxygen species regulate acetyl-CoA flux between cytokine production and fatty acid synthesis in effector T cells

By sjmartinez • March 17, 2025

Wu B, Woo JS, Hasiakos S, Pan C, Cokus S, Benincá C, Stiles L, Sun Z, Pellegrini M, Shirihai OS, Lusis AJ, Srikanth S, Gwack Y. Mitochondrial reactive oxygen species regulate acetyl-CoA flux between cytokine production and fatty acid synthesis in effector T cells. Cell Rep. 2025 Mar 13;44(3):115430. doi: 10.1016/j.celrep.2025.115430. Epub ahead of print. PMID: 40088449.

Tags: Cardiology/Epi, CP: Immunology, CP: Metabolism, cytokine production, EAE, Endocrinology, histone acetylation, MICOS complex, mitochondria, mitochondrial cristae architecture, neutral lipids, Publications, reactive oxygen species, Th1 cells

Outcomes of Early Sodium-Glucose Cotransporter 2 Inhibitor Use in Takotsubo Syndrome: Insights from a Multicenter Real-World Cohort Study

Taha A, Mondal A, Sandhyavenu H, Atti L, Alhajji M, Thangjui S, Shaik BF, Thyagaturu H, Caccamo M, Fonarow GC, Balla S. Outcomes of Early[...]

In-Hospital Stroke Quality and Outcomes in the Mechanical Thrombectomy Era: Get With The Guidelines-Stroke, 2016 to 2023

Nouh A, Olson D, Liang H, Koriesh A, Ali M, Bashir MMI, Mukerjee P, Man S, Fonarow GC. In-Hospital Stroke Quality and Outcomes in the[...]

Clinical Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors Among Older Patients Hospitalized for Heart Failure With Reduced Ejection Fraction

Brownell N, Solomon N, Greene SJ, Chiswell K, Vaduganathan M, Yancy C, Hsue P, Ziaeian B, Fonarow GC. Clinical Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors Among[...]