Prostaglandin E2 and Akt promote stemness in Apc mutant Dclk1+ cells to give rise to colitis-associated cancer

By sjmartinez • January 31, 2025

Good HJ, Larsen F, Shin AE, Zhang L, Derouet M, Meriwether D, Worthley D, Reddy ST, Wang TC, Asfaha S. Prostaglandin E₂ and Akt promote stemness in Apc mutant Dclk1+ cells to give rise to colitis-associated cancer. Cell Mol Gastroenterol Hepatol. 2025 Jan 28:101469. doi: 10.1016/j.jcmgh.2025.101469. Epub ahead of print. PMID: 39884575.

Tags: Aspirin, Cardiology/Epi, colitis, Colon cancer, Dclk1, Digestive Diseases, Publications, Stem cells

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