Prostaglandin E2 and Akt promote stemness in Apc mutant Dclk1+ cells to give rise to colitis-associated cancer

Good HJ, Larsen F, Shin AE, Zhang L, Derouet M, Meriwether D, Worthley D, Reddy ST, Wang TC, Asfaha S. Prostaglandin E2 and Akt promote stemness in Apc mutant Dclk1+ cells to give rise to colitis-associated cancer. Cell Mol Gastroenterol Hepatol. 2025 Jan 28:101469. doi: 10.1016/j.jcmgh.2025.101469. Epub ahead of print. PMID: 39884575.


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