Antibody ligation of HLA class II induces YAP nuclear localization and formation of cytoplasmic YAP condensates in human endothelial cells

By sjmartinez • January 27, 2025

Lone M, Anwar T, Sinnett-Smith J, Jin YP, Reed EF, Rozengurt E. Antibody ligation of HLA class II induces YAP nuclear localization and formation of cytoplasmic YAP condensates in human endothelial cells. Immunohorizons. 2025 Jan 27;9(3):vlae008. doi: 10.1093/immhor/vlae008. PMID: 39865973.

Tags: cytoplasmic puncta, Digestive Diseases, Hippo pathway, HLA class II antibodies, Post Doc, Publications, transplant rejection

Gastro Grand Rounds:Managing Complex IBS: A Multidisciplinary, Mechanism-Based Approach

Chang L, Bedell A, Smith J, Smith S, Lembo A. Gastro Grand Rounds:Managing Complex IBS: A Multidisciplinary, Mechanism-Based Approach. Gastroenterology. 2026 Aug 4:S0016-5085(26)07124-6. doi: 10.1053/j.gastro.2026.07.018.[...]

Rectal Ulceration as an Atypical Initial Gastrointestinal Manifestation of Advanced HIV Infection: A Case Report

Verhaegh T, Panossian A, Skay AN, Ilyas Z, Namavar AA. Rectal Ulceration as an Atypical Initial Gastrointestinal Manifestation of Advanced HIV Infection: A Case Report.[...]

From tissue to blood: an integrated multi-omics signature identifies fibrogenesis and neutrophil activation as key drivers of ulcerative colitis severity

Ozcariz E, Ostaszewski M, Lopata O, Ciglar L, Li Yim AYF, Pruijt M, Wang X, Vignolle GA, Tran F, Satagopam V, D'Haens GR, Schreiber S,[...]