Sometimes Small Is Beautiful: Discovery of the Janus Kinases (JAK) and Signal Transducer and Activator of Transcription (STAT) Pathways and the Initial Development of JAK Inhibitors for IBD Treatment

By sjmartinez • January 21, 2025

Kaunitz JD. Sometimes Small Is Beautiful: Discovery of the Janus Kinases (JAK) and Signal Transducer and Activator of Transcription (STAT) Pathways and the Initial Development of JAK Inhibitors for IBD Treatment. Dig Dis Sci. 2025 Jan 18. doi: 10.1007/s10620-024-08791-1. Epub ahead of print. PMID: 39827247.

Tags: Cytokines, Digestive Diseases, interferons, Interleukins, JAK/STAT pathway, JAKininbs, Publications, tofacitinib, Veterans Administration

Topic Mapping to Inform Content to Discuss in Shared Decision-Making for Prostate Cancer

Friedrich NA, Kokorowski P, Luu M, Chaplin A, Polineni R, Shiang A, Shin D, Tan J, Freedland SJ, Spiegel B, Daskivich TJ. Topic Mapping to[...]

Gluten-Associated Neurological Disorders: A Cases Series

Bachu VS, Ghodrati F, Fogel BL, Weiss GA. Gluten-Associated Neurological Disorders: A Cases Series. Case Rep Gastroenterol. 2025 May 29;19(1):387-391. doi: 10.1159/000544765. PMID: 40444061; PMCID:[...]

Secondary Spontaneous Bacterial Peritonitis Prophylaxis Is Associated With a Higher Rate of Infections other than Spontaneous Bacterial Peritonitis in 2 US-Based National Cirrhosis Cohorts

Silvey S, Patel N, O'Leary JG, Jakab SS, Patton H, Rogal S, Markley JD, Cheung R, Patel A, Morgan TR, Bajaj JS. Secondary Spontaneous Bacterial[...]