Optimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2

By sjmartinez • January 18, 2025

Sen C, Rickabaugh TM, Jeyachandran AV, Yuen C, Ghannam M, Durra A, Aziz A, Castillo K, Garcia G Jr, Purkayastha A, Han B, Boulton FW, Chekler E, Garces R, Wolff KC, Riva L, Kirkpatrick MG, Gebara-Lamb A, McNamara CW, Betz UAK, Arumugaswami V, Damoiseaux R, Gomperts BN. Optimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2. Respir Res. 2025 Jan 16;26(1):18. doi: 10.1186/s12931-025-03095-y. PMID: 39819574; PMCID: PMC11740480.

Tags: Air–liquid-interface, Anti-viral screening, heterogeneity, High throughput drug screening, Human mucociliary epithelium, Image quantification, Publications, Pulmonary, Critical Care & Sleep Medicine, Respiratory viral infections, RNA sequencing, SARS-CoV-2, Small-molecules

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