Wip1 phosphatase activator QGC-8-52 specifically sensitizes p53-negative cancer cells to chemotherapy while protecting normal cells

By sjmartinez • January 10, 2025

Wu K, Ge XX, Duan XF, Li JQ, Wang K, Chen QH, Huang ZM, Zhang WY, Wu Y, Li Q. Wip1 phosphatase activator QGC-8-52 specifically sensitizes p53-negative cancer cells to chemotherapy while protecting normal cells. Drug Resist Updat. 2024 Dec 24;79:101196. doi: 10.1016/j.drup.2024.101196. Epub ahead of print. PMID: 39787991.

Tags: breast cancer, Dephosphorylation, FOXO3a, General Internal Medicine, King Drew Med Ctr, Post Doc, Publications, TRAIL, Wip1

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