TOP1 Mutations and Cross-Resistance to Antibody-Drug Conjugates in Patients with Metastatic Breast Cancer

Abelman RO, Wu B, Barnes H, Medford A, Norden B, Putur A, Bitman E, Thant W, Liu T, Weipert C, Fell G, Spring LM, Wander S, Moy B, Vidula N, Isakoff SJ, Varkaris A, Juric D, Corcoran R, Ellisen LW, Bardia A. TOP1 Mutations and Cross-Resistance to Antibody-Drug Conjugates in Patients with Metastatic Breast Cancer. Clin Cancer Res. 2025 Jan 2. doi: 10.1158/1078-0432.CCR-24-2771. Epub ahead of print. PMID: 39745368.


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