Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny

By sjmartinez • December 17, 2024

Vandiver AR, Torres A Jr, Sanden A, Nguyen TL, Gasilla J, Doan MT, Martirosian V, Hoang A, Wanagat J, Teitell MA. Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny. Aging Cell. 2024 Dec 16:e14402. doi: 10.1111/acel.14402. Epub ahead of print. PMID: 39680477.

Tags: Aging, Dermatology, Geriatrics, iPSC, mitochondria, mtDNA, mutation, Publications, Veterans Administration

Exacerbation of bullous systemic lupus erythematosus with erythema gyratum repens-like pattern following dupilumab

Santiago Mangual KP, Truong A, Mo J, Liu J, Khaligi MA, Haussmann A, Razmjou AA, Holland V, Cheng K. Exacerbation of bullous systemic lupus erythematosus[...]

Chronic companions: An updated national cross-sectional study of metabolic syndrome comorbidities in outpatient visits for hidradenitis suppurativa

Ma EJ, Roberts AM, Chou P, Katz A, Jeong CY, Nong Y, Ochoa MT, Armstrong AW. Chronic companions: An updated national cross-sectional study of metabolic[...]

Anchored Matching-Adjusted Indirect Comparison of the Long-Term Maintenance of Efficacy of Tralokinumab and Lebrikizumab in Patients with Moderate-to-Severe Atopic Dermatitis

Augustin M, Armstrong A, Issa NT, Petersen AS, von Eyben R, Festini T, Torres T. Anchored Matching-Adjusted Indirect Comparison of the Long-Term Maintenance of Efficacy[...]