Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny

By sjmartinez • December 17, 2024

Vandiver AR, Torres A Jr, Sanden A, Nguyen TL, Gasilla J, Doan MT, Martirosian V, Hoang A, Wanagat J, Teitell MA. Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny. Aging Cell. 2024 Dec 16:e14402. doi: 10.1111/acel.14402. Epub ahead of print. PMID: 39680477.

Tags: Aging, Dermatology, Geriatrics, iPSC, mitochondria, mtDNA, mutation, Publications, Veterans Administration

Epigenetic age and accelerated aging phenotypes: a tumor biomarker for predicting colorectal cancer

Jung SY, Pellegrini M, Tan X, Yu H. Epigenetic age and accelerated aging phenotypes: a tumor biomarker for predicting colorectal cancer. Aging (Albany NY). 2025[...]

Macrophage-derived Spp1 promotes intramuscular fat in dystrophic muscle

Farahat PK, Kumagai-Cresse C, Aragón RL, Ma F, Amakor JK, Espinoza A, Kramerova I, Jimenez RJ, Smith BM, Perez J, Crosbie RH, Nagendra AH, McCourt-Towner[...]

AI-Assisted Billing in Dermatologic Surgery: Evaluating ChatGPT’s and Gemini’s Accuracy in CPT Code Assignment

Modiri O, Ebriani J, Jairath N, Lewin J. AI-Assisted Billing in Dermatologic Surgery: Evaluating ChatGPT's and Gemini's Accuracy in CPT Code Assignment. Dermatol Surg. 2025[...]