Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny

By sjmartinez • December 17, 2024

Vandiver AR, Torres A Jr, Sanden A, Nguyen TL, Gasilla J, Doan MT, Martirosian V, Hoang A, Wanagat J, Teitell MA. Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny. Aging Cell. 2024 Dec 16:e14402. doi: 10.1111/acel.14402. Epub ahead of print. PMID: 39680477.

Tags: Aging, Dermatology, Geriatrics, iPSC, mitochondria, mtDNA, mutation, Publications, Veterans Administration

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