HLA class I antibody-activated endothelium promotes CD206+ M2-macrophage polarization and MMP9 secretion through TLR4 signaling and P-selectin in a model of antibody-mediated rejection and allograft vasculopathy

By sjmartinez • November 4, 2024

Nevarez-Mejia J, Jin YP, Pickering H, Parmar R, Valenzuela NM, Sosa RA, Heidt S, Fishbein GA, Rozengurt E, William MB 3rd, Fairchild RL, Reed EF. HLA class I antibody-activated endothelium promotes CD206+ M2-macrophage polarization and MMP9 secretion through TLR4 signaling and P-selectin in a model of antibody-mediated rejection and allograft vasculopathy. Am J Transplant. 2023 Oct 27:S1600-6135(23)00822-5. doi: 10.1016/j.ajt.2023.10.020. Epub ahead of print. PMID: 39491096.

Tags: Digestive Diseases, Publications

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