Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation

By sjmartinez • October 27, 2024

Zhang T, Chen J, Yang H, Sun X, Ou Y, Wang Q, Edderkaoui M, Zheng S, Ren F, Tong Y, Hu R, Liu J, Gao Y, Pandol SJ, Han YP, Zheng X. Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation. Cell Mol Life Sci. 2024 Oct 26;81(1):442. doi: 10.1007/s00018-024-05466-y. PMID: 39460766; PMCID: PMC11512982.

Tags: Autophagy, Cedars Sinai DoM, Digestive Diseases, Olive View DoM, pancreatic ductal adenocarcinoma, Publications, Soft matrix, Tumor dormancy, Yes-associated protein 1

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