Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation

By sjmartinez • October 27, 2024

Zhang T, Chen J, Yang H, Sun X, Ou Y, Wang Q, Edderkaoui M, Zheng S, Ren F, Tong Y, Hu R, Liu J, Gao Y, Pandol SJ, Han YP, Zheng X. Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation. Cell Mol Life Sci. 2024 Oct 26;81(1):442. doi: 10.1007/s00018-024-05466-y. PMID: 39460766; PMCID: PMC11512982.

Tags: Autophagy, Cedars Sinai DoM, Digestive Diseases, Olive View DoM, pancreatic ductal adenocarcinoma, Publications, Soft matrix, Tumor dormancy, Yes-associated protein 1

Related Posts

Design of Screening Cardiometabolic Opportunities Using Transformative Echocardiography Artificial Intelligence (SCOUT-Echo-AI)

Eusuff S, Kim J, Fatima Z, Yalcinkaya D, Sahashi Y, Sandhu A, Nguyen LH, Ambrosy AP, Cheng PP, Chang ST, Go AS, Ahmad FS, Cheung[...]

A Single-Cell Atlas of Diabetes-Associated Remodeling in the Human Corneal Limbus

Zha D, Wang Y, Shah R, Ebrahimi SM, Poe AJ, Amador C, Inzalaco J, Fealy A, Sawant OB, Kramerov AA, Wang ZP, Ljubimov AV, Saghizadeh[...]

Use of Myocardial Perfusion Imaging to Guide Prognosis and Management in Older Adults: Is There an Age Limit?

Patel KK, Miller RJH, Lemley M, Shanbhag A, Ramirez G, Liang JX, Acampa W, Bateman TM, Dorbala S, Einstein AJ, Hauser MT, Kaufmann PA, Feher[...]