Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation

By sjmartinez • October 27, 2024

Zhang T, Chen J, Yang H, Sun X, Ou Y, Wang Q, Edderkaoui M, Zheng S, Ren F, Tong Y, Hu R, Liu J, Gao Y, Pandol SJ, Han YP, Zheng X. Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation. Cell Mol Life Sci. 2024 Oct 26;81(1):442. doi: 10.1007/s00018-024-05466-y. PMID: 39460766; PMCID: PMC11512982.

Tags: Autophagy, Cedars Sinai DoM, Digestive Diseases, Olive View DoM, pancreatic ductal adenocarcinoma, Publications, Soft matrix, Tumor dormancy, Yes-associated protein 1

Comprehensive echocardiogram evaluation with view primed vision language AI

Vukadinovic M, Chiu IM, Tang X, Yuan N, Chen TY, Cheng P, Li D, Cheng S, He B, Ouyang D. Comprehensive echocardiogram evaluation with view[...]

Racial and Ethnic Disparities in Pandemic-Onset Disorders of Gut-Brain Interaction: Results From a Nationwide Survey

Yang Y, Spiegel BMR, Chey WD, Choi SY, Almario CV. Racial and Ethnic Disparities in Pandemic-Onset Disorders of Gut-Brain Interaction: Results From a Nationwide Survey.[...]

TH17 cells converted into exTH17 cells sustain rheumatoid-like IL-17-independent inflammatory arthritis

Zoccheddu M, Suga K, Seng A, Svensson MND, Dutta P, Panahandeh S, Makinde HM, Ro M, Wang Y, Kim H, Mikulski Z, Dobaczewska K, Ingegnoli[...]