Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response

By sjmartinez • September 3, 2024

An J, Kurilov R, Peccerella T, Bergmann F, Edderkaoui M, Lim A, Zhou X, Pfütze K, Schulz A, Wolf S, Hu K, Springfeld C, Mughal SS, Zezlina L, Fortunato F, Beyer G, Mayerle J, Roth S, Hulkkonen J, Merz D, Ei S, Mehrabi A, Loos M, Al-Saeedi M, Michalski CW, Büchler MW, Hackert T, Brors B, Pandol SJ, Bailey P, Neoptolemos JP. Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response. Transl Oncol. 2024 Aug 31;49:102109. doi: 10.1016/j.tranon.2024.102109. Epub ahead of print. PMID: 39217851.

Tags: apoptosis, Autophagy, Cedars Sinai DoM, Digestive Diseases, GSK3-β, Histone deacetylases, Molecular subtypes, pancreatic cancer, Publications

Related Posts

Value of HCC surveillance in a landscape of emerging surveillance options: Perspectives of a multi-stakeholder modified Delphi panel

Singal AG, Quirk L, Boike J, Chernyak V, Feng Z, Giamarqo G, Kanwal F, Ioannou GN, Manes S, Marrero JA, Mehta N, Pillai A, Shaheen[...]

Integrated molecular and clinical characterization of pulmonary large cell neuroendocrine carcinoma

Nassar AH, Kim C, Adeyelu T, Bou Farhat E, Abushukair H, Rakaee M, Matteson K, Lau SF, Takabe Y, Ocejo A, Ardeshir-Larijani F, Leal T,[...]

Accelerated 3D qCEST of the Spine in a Porcine Model Using MR Multitasking at 3T

Cheema K, De Righi DR, Shen C, Lee HL, Kaneda G, Wechsler J, Chavez M, Avalos P, Floyd C, Tawackoli W, Xie Y, Christodoulou AG,[...]