Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma

By sjmartinez • September 1, 2024

Long D Jr, Chan M, Han M, Kamdar Z, Ma RK, Tsai PY, Francisco AB, Barrow J, Shackelford DB, Yarchoan M, McBride MJ, Orre LM, Vacanti NM, Gujral TS, Sethupathy P. Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma. Cell Rep Med. 2024 Aug 21:101699. doi: 10.1016/j.xcrm.2024.101699. Epub ahead of print. PMID: 39208801.

Tags: alpha-ketoglutarate, fibrolamellar carcinoma, glucose, glutamine, metabolomics, mitochondria, proline, proteomics, Publications, Pulmonary, Critical Care & Sleep Medicine, pyruvate, serine

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