Dysregulation of cholesterol homeostasis is an early signal of β-cell proteotoxicity characteristic of type 2 diabetes

By sjmartinez • August 23, 2024

Gurlo T, Liu R, Wang Z, Hoang J, Ryazantsev S, Daval M, Butler AE, Yang X, Blencowe M, Butler PC. Dysregulation of cholesterol homeostasis is an early signal of β-cell proteotoxicity characteristic of type 2 diabetes. Physiol Genomics. 2024 Sep 1;56(9):621-633. doi: 10.1152/physiolgenomics.00029.2024. Epub 2024 Jul 1. PMID: 38949617.

Tags: Cholesterol, Endocrinology, islet amyloid polypeptide, Publications, RNA-seq, Type 2 diabetes, β-cell

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