1. < Cedars Sinai DoM

Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness

By sjmartinez • August 22, 2024

Hatziapostolou M, Koutsioumpa M, Zaitoun AM, Polytarchou C, Edderkaoui M, Mahurkar-Joshi S, Vadakekolathu J, D'Andrea D, Lay AR, Christodoulou N, Pham T, Yau TO, Vorvis C, Chatterji S, Pandol SJ, Poultsides GA, Dawson DW, Lobo DN, Iliopoulos D. Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness. Gastro Hep Adv. 2024 Apr 24;3(5):687-702. doi: 10.1016/j.gastha.2024.04.005. PMID: 39165427; PMCID: PMC11330932.

Tags: Cedars Sinai DoM, Digestive Diseases, DNA methylation, epigenetics, HNF4A, pancreatic cancer, Publications

Related Posts

Allele-specific dysregulation of lipid and energy metabolism in early-stage hypertrophic cardiomyopathy

Vaniya A, Karlstaedt A, Gulkok D, Thottakara T, Liu Y, Fan S, Eades H, Vakrou S, Fukunaga R, Vernon HJ, Fiehn O, Roselle Abraham M.[...]

Design and Rationale of a Pragmatic Randomized Clinical Trial of Early Dronedarone versus Usual Care to Change and Improve Outcomes in Persons with First-Detected Atrial Fibrillation – The CHANGE AFIB Study

Pokorney SD, Nemeth H, Chiswell K, Albert C, Allyn N, Blanco R, Butler J, Calkins H, Elkind MSV, Fonarow GC, Fontaine JM, Frankel DS, Fermann[...]

Integrating priorities at the intersection of cancer and neuroscience

Hwang WL, Perrault EN, Birbrair A, Mattson BJ, Gutmann DH, Mabbott DJ, Cukierman E, Repasky EA, Sloan EK, Zong H, Demir IE, Saloman JL, Borniger[...]