A pathologically expanded, clonal lineage of IL-21-producing CD4+ T cells drives inflammatory neuropathy

By sjmartinez • August 2, 2024

Seyedsadr M, Bang MF, McCarthy EC, Zhang S, Chen HC, Mohebbi M, Hugo W, Whitmire JK, Lechner MG, Su MA. A pathologically expanded, clonal lineage of IL-21-producing CD4+ T cells drives inflammatory neuropathy. J Clin Invest. 2024 Jun 11;134(15):e178602. doi: 10.1172/JCI178602. PMID: 39087473; PMCID: PMC11290969.

Tags: Autoimmune Diseases, autoimmunity, Cytokines, Dermatology, Immunology, Publications, T cells

Cathepsin C (dipeptidyl peptidase 1) inhibition in adults with bronchiectasis: AIRLEAF®, a Phase II randomised, double-blind, placebo-controlled, dose-finding study

Chalmers JD, Shteinberg M, Mall MA, O'Donnell AE, Watz H, Gupta A, Frahm E, Eleftheraki A, Rauch J, Chotirmall SH, Armstrong AW, Eickholz P, Hasegawa[...]

Genome of Dietzia cinnamea 55, a desert-isolated microbe with plant growth-promoting properties for grain crops

Hirsch AM, Khan N, Humm E, Rubbi M, Del Vecchio G, Ha SM, Pellegrini M, Gunsalus RP. Genome of Dietzia cinnamea 55, a desert-isolated microbe with plant[...]

Identifying Predictors of PASI100 Responses up to Month 12 in Patients with Moderate-to-severe Psoriasis Receiving Biologics in the Psoriasis Study of Health Outcomes (PSoHO)

Armstrong AW, Riedl E, Brunner PM, Piaserico S, Visser WI, Haustrup N, Konicek BW, Kadziola Z, Nunez M, Brnabic A, Schuster C. Identifying Predictors of[...]