Unveiling promising drug targets for autism spectrum disorder: insights from genetics, transcriptomics, and proteomics

By sjmartinez • July 23, 2024

Jiang R, Huang W, Qiu X, Chen J, Luo R, Zeng R, Tong S, Lyu Y, Sun P, Lian Q, Leung FW, Liu Y, Sha W, Chen H. Unveiling promising drug targets for autism spectrum disorder: insights from genetics, transcriptomics, and proteomics. Brief Bioinform. 2024 May 23;25(4):bbae353. doi: 10.1093/bib/bbae353. PMID: 39038939.

Tags: autism spectrum disorder, Digestive Diseases, drug target prediction, Mendelian randomization, Publications, Veterans Administration

Targeting lipidated amino acid deficiency mitigates fibrosis via a PPARα/CCL2 axis in metabolic dysfunction-associated steatohepatitis models

Anand SK, Das S, Arias F, Richard KS, Rohilla S, Ghrayeb A, McKinney MP, Wang L, Tan L, Ding J, Kumar D, Pandey N, Lee[...]

Fibroblasts restrain gut inflammation by IGF1-dependent regulation of innate lymphocytes

Lin Q, Liu RE, Wang Q, Kang L, Chen B, Lu Y, Zhang Y, Gu Z, Zhou Y, Liu H, Xu X, Cao Z, Tang[...]

Healthy donor faecal microbiota transplantation in irritable bowel syndrome: interpreting negative findings

Liu J, Shin A. Healthy donor faecal microbiota transplantation in irritable bowel syndrome: interpreting negative findings. Lancet. 2026 Sep 24:S0140-6736(26)01815-5. doi: 10.1016/S0140-6736(26)01815-5. Epub ahead of[...]