SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback

By sjmartinez • July 23, 2024

Bloom N, Ramirez SI, Cohn H, Parikh UM, Heaps A, Sieg SF, Greninger A, Ritz J, Moser C, Eron JJ, Bajic G, Currier JS, Klekotka P, Wohl DA, Daar ES, Li J, Hughes MD, Chew KW, Smith DM, Crotty S, Coelho CH; Accelerating COVID-19 Therapeutic Interventions and Vaccines–2/A5401 (ACTIV-2/A5401) Study Team. SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback. J Infect Dis. 2024 Jul 22:jiae371. doi: 10.1093/infdis/jiae371. Epub ahead of print. PMID: 39036987.

Tags: bamlanivimab, covid-19, Harbor UCLA, Infectious Diseases, mAb therapy, memory B cells, Publications, SARS-CoV-2

ACTIV trials: cross-trial lessons learned for master protocol implementation

Keshtkar-Jahromi M, Adam SJ, Brar I, Chung LK, Currier JS, Daar ES, Davey VJ, Denning ET, Gelijns AC, Higgs ES, Jagannathan P, Javan AC, Jensen[...]

Hypokalemic periodic paralysis presenting as cardiac arrest

Joshi M, Salameh W, Vintch J, Goodman EL. Hypokalemic periodic paralysis presenting as cardiac arrest. BMJ Case Rep. 2024 Nov 13;17(11):e259889. doi: 10.1136/bcr-2024-259889. PMID: 39537393.

Aquaporin-4 Immunoglobulin G-seropositive Neuromyelitis Optica Spectrum Disorder MRI Characteristics: Data Analysis from the International Real-World PAMRINO Study Cohort

Chien C, Cruz E Silva V, Geiter E, Meier D, Zimmermann H, Bichuetti DB, Idagawa MI, Altintas A, Tanriverdi U, Siritho S, Pandit L, Dcunha[...]