SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback

By sjmartinez • July 23, 2024

Bloom N, Ramirez SI, Cohn H, Parikh UM, Heaps A, Sieg SF, Greninger A, Ritz J, Moser C, Eron JJ, Bajic G, Currier JS, Klekotka P, Wohl DA, Daar ES, Li J, Hughes MD, Chew KW, Smith DM, Crotty S, Coelho CH; Accelerating COVID-19 Therapeutic Interventions and Vaccines–2/A5401 (ACTIV-2/A5401) Study Team. SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback. J Infect Dis. 2024 Jul 22:jiae371. doi: 10.1093/infdis/jiae371. Epub ahead of print. PMID: 39036987.

Tags: bamlanivimab, covid-19, Harbor UCLA, Infectious Diseases, mAb therapy, memory B cells, Publications, SARS-CoV-2

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