Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions

By sjmartinez • June 4, 2024

Lo CH, O'Connor LM, Loi GWZ, Saipuljumri EN, Indajang J, Lopes KM, Shirihai OS, Grinstaff MW, Zeng J. Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions. ACS Nano. 2024 Jun 3. doi: 10.1021/acsnano.3c09206. Epub ahead of print. PMID: 38830624.

Tags: acidic nanoparticles, autophagic degradation, Endocrinology, insulin secretion, lysosomal acidification, mitochondrial function, Publications, T2D, Type 2 diabetes, V-ATPase

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