Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions

By sjmartinez • June 4, 2024

Lo CH, O'Connor LM, Loi GWZ, Saipuljumri EN, Indajang J, Lopes KM, Shirihai OS, Grinstaff MW, Zeng J. Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions. ACS Nano. 2024 Jun 3. doi: 10.1021/acsnano.3c09206. Epub ahead of print. PMID: 38830624.

Tags: acidic nanoparticles, autophagic degradation, Endocrinology, insulin secretion, lysosomal acidification, mitochondrial function, Publications, T2D, Type 2 diabetes, V-ATPase

Related Posts

Oxidative stress-regulatory role of miR-10b-5p in the diabetic human cornea revealed through integrated multi-omics analysis

Zha D, Gamez J, Ebrahimi SM, Wang Y, Verma N, Poe AJ, White S, Shah R, Kramerov AA, Sawant OB, Santiskulvong C, Stotland AB, Wang[...]

The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson’s disease mouse model

Morais LH, Stiles L, Freeman M, Oguienko AD, Hoang JD, Ji J, Jones J, Quan B, Devine J, Bois JS, Chou TF, Trinh J, Picard[...]

Consensus-based disease definitions for endocrine immune-related adverse events of immune checkpoint inhibitors

Zhu L, Cheung YM, Chiang C, Gallagher EJ, Hamnvik OR, Mammen J, Quandt Z, Jones R, McDunn J, Al-Bahadili H, Angell T, Bancos I, Betof[...]