Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity

By sjmartinez • April 17, 2024

Chen YQ, Yang Y, Zhen EY, Beyer TP, Li H, Wen Y, Ehsani M, Jackson N, Xie K, Jung H, Scheithauer JL, Kumari A, Birrane G, Russell AM, Balasubramaniam D, Liao Z, Siegel RW, Qian Y, Ploug M, Young SG, Konrad RJ. Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2322332121. doi: 10.1073/pnas.2322332121. Epub 2024 Apr 16. PMID: 38625948.

Tags: ANGPTL3/8, apolipoprotein AV, Cardiology/Epi, General Internal Medicine, lipoprotein lipase, Publications, triglycerides

The noncanonical NFκB pathway: Regulatory mechanisms in health and disease

Rodriguez BN, Huang H, Chia JJ, Hoffmann A. The noncanonical NFκB pathway: Regulatory mechanisms in health and disease. WIREs Mech Dis. 2024 Nov-Dec;16(6):e1646. doi: 10.1002/wsbm.1646.[...]

Acute Coronary Syndrome in Women

Cader FA, Sareen N, Press MC. Acute Coronary Syndrome in Women. Interv Cardiol Clin. 2025 Jan;14(1):9-19. doi: 10.1016/j.iccl.2024.08.011. PMID: 39537292.

The Rebirth of Intraoperative Electrophysiological Mapping for Complex Congenital Heart Disease

Moore JP, Shivkumar K. The Rebirth of Intraoperative Electrophysiological Mapping for Complex Congenital Heart Disease. J Am Coll Cardiol. 2024 Nov 19;84(21):2113-2115. doi: 10.1016/j.jacc.2024.08.078. PMID:[...]