Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity

By sjmartinez • April 17, 2024

Chen YQ, Yang Y, Zhen EY, Beyer TP, Li H, Wen Y, Ehsani M, Jackson N, Xie K, Jung H, Scheithauer JL, Kumari A, Birrane G, Russell AM, Balasubramaniam D, Liao Z, Siegel RW, Qian Y, Ploug M, Young SG, Konrad RJ. Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2322332121. doi: 10.1073/pnas.2322332121. Epub 2024 Apr 16. PMID: 38625948.

Tags: ANGPTL3/8, apolipoprotein AV, Cardiology/Epi, General Internal Medicine, lipoprotein lipase, Publications, triglycerides

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