Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells

By sjmartinez • April 8, 2024

Carrillo MA, Zhen A, Mu W, Rezek V, Martin H, Peterson CW, Kiem HP, Kitchen SG. Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells. Mol Ther. 2024 Apr 3;32(4):1000-1015. doi: 10.1016/j.ymthe.2024.02.026. Epub 2024 Feb 27. PMID: 38414243.

Tags: adoptive cell therapy, CAR T cells, Hematology/Oncology, HIV, humanized mouse model, nonhuman primate model, Publications, stem cell gene therapy

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