CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer

By sjmartinez • March 23, 2024

Lim RJ, Salehi-Rad R, Tran LM, Oh MS, Dumitras C, Crosson WP, Li R, Patel TS, Man S, Yean CE, Abascal J, Huang Z, Ong SL, Krysan K, Dubinett SM, Liu B. CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer. Cell Rep Med. 2024 Mar 19:101479. doi: 10.1016/j.xcrm.2024.101479. Epub ahead of print. PMID: 38518770.

Tags: Checkpoint blockade, CXCL10, CXCL9, CXCR3, dendritic cells, Fellow, Hematology/Oncology, immunosuppression, in situ vaccination, NSCLC, Publications, Pulmonary, Critical Care & Sleep Medicine, Resident, systemic immunity, T cells, Veterans Administration

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