Hevener Lab Research

By sjmartinez • March 11, 2024

Skeletal muscle action of estrogen receptor a is critical for maintenance of mitochondrial function and metabolic homeostasis in females

V. Ribas, B. G. Drew, Z. Zhou, J. Phun, N. Y. Kalajian, T. Soleymani, P. Daraei, K. Widjaja, J. Wanagat, T. Q. de Aguiar Vallim, A. H. Fluitt, S. Bensinger, T. Le, C. Radu, J. P. Whitelegge, S. W. Beaven, P. Tontonoz, A. J. Lusis, B. W. Parks, L. Vergnes, K. Reue, H. Singh, J. C. Bopassa, L. Toro, E. Stefani, M. J. Watt, S. Schenk, T. Akerstrom, M. Kelly, B. K. Pedersen, S. C. Hewitt, K. S. Korach, A. L. Hevener, Skeletal muscle action of estrogen receptor a is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Sci. Transl. Med. 8, 334ra54 (2016).

Estrogen receptor a controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling

Z. Zhou, T. M. Moore, B. G. Drew, V. Ribas, J. Wanagat, M. Civelek, M. Segawa, D. M. Wolf, F. Norheim, M. M. Seldin, A. R. Strumwasser, K. A. Whitney, E. Lester, B. R. Reddish, L. Vergnes, K. Reue, P. Rajbhandari, P. Tontonoz, J. Lee, S. K. Mahata, S. C. Hewitt, O. Shirihai, C. Gastonbury, K. S. Small, M. Laakso, J. Jensen, S. Lee, C. A. Drevon, K. S. Korach, A. J. Lusis, A. L. Hevener, Estrogen receptor  controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling. Sci. Transl. Med. 12, eaax8096 (2020).

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