Human leukocyte antigen class I antibody-activated endothelium promotes CD206+ M2 macrophage polarization and MMP9 secretion through TLR4 signaling and P-selectin in a model of antibody-mediated rejection and allograft vasculopathy

By sjmartinez • February 22, 2024

Nevarez-Mejia J, Jin YP, Pickering H, Parmar R, Valenzuela NM, Sosa RA, Heidt S, Fishbein GA, Rozengurt E, Baldwin WM 3rd, Fairchild RL, Reed EF. Human leukocyte antigen class I antibody-activated endothelium promotes CD206+ M2 macrophage polarization and MMP9 secretion through TLR4 signaling and P-selectin in a model of antibody-mediated rejection and allograft vasculopathy. Am J Transplant. 2023 Oct 29:S1600-6135(23)00822-5. doi: 10.1016/j.ajt.2023.10.020. Epub ahead of print. PMID: 38379280.

Tags: AMR, antibody-mediated rejection, AOIs, areas of interest, cardiac allograft vasculopathy, CAV, Digestive Diseases, donor-specific HLA antibodies, DSA, EC, endothelial cell, HLA, human leukocyte antigen, Publications, transplant vasculopathy, TV

Extraintestinal symptoms in irritable bowel syndrome are associated with stress reactivity and the gut microbiome in a sex-dependent manner

Jacobs JP, Labus JS, Dong TS, Shin AS; UCLA SCORE Group in IBS and Sex Differences; Mayer EA, Chang L. Extraintestinal symptoms in irritable bowel[...]

Colonoscopic Follow-up After Abnormal Blood-Based Colorectal Cancer Screening Results

Zaki TA, Zhang NJ, Forbes SP, Raymond VM, Das AK, May FP. Colonoscopic Follow-up After Abnormal Blood-Based Colorectal Cancer Screening Results. Gastroenterology. 2025 Jul 21:S0016-5085(25)05775-0.[...]

The triple-effect of colorectal cancer screening: reducing deaths, government spending and mortality disparities

Nascimento De Lima P, Bartholomew L, May FP, Coronado GD, Rutter CM. The triple-effect of colorectal cancer screening: reducing deaths, government spending and mortality disparities.[...]