Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes

By sjmartinez • February 3, 2024

Zhang Y, Bharathi V, Dokoshi T, de Anda J, Ursery LT, Kulkarni NN, Nakamura Y, Chen J, Luo EWC, Wang L, Xu H, Coady A, Zurich R, Lee MW, Matsui T, Lee H, Chan LC, Schepmoes AA, Lipton MS, Zhao R, Adkins JN, Clair GC, Thurlow LR, Schisler JC, Wolfgang MC, Hagan RS, Yeaman MR, Weiss TM, Chen X, Li MMH, Nizet V, Antoniak S, Mackman N, Gallo RL, Wong GCL. Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2300644120. doi: 10.1073/pnas.2300644120. Epub 2024 Feb 2. PMID: 38306481.

Tags: antimicrobial peptides, Harbor UCLA, Infectious Diseases, Inflammation, Molecular Medicine, polyelectrolytes, Publications, self-assembly, superselectivity

Efficacy of an oral lipid nanocrystal formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis

Gu Y, Gebremariam T, Alkhazraji S, Youssef E, El-Gamal S, Matkovits T, Cobb J, Mannino R, Ibrahim AS. Efficacy of an oral lipid nanocrystal formulation[...]

A Leaky False Pouch: Left Ventricle Pseudoaneurysm with Active Hemopericardium Detected on Cardiac Computed Tomography Angiography

Barforoshi S, Shekar C, Yu Z, Liu E, Manubolu V, Budoff MJ, Roy SK. A Leaky False Pouch: Left Ventricle Pseudoaneurysm with Active Hemopericardium Detected[...]

Comparing Cardiovascular Events Across Home Dialysis Modalities: Adjusting the Unadjustable?

Nadeau-Fredette AC, Shen JI, Perl J. Comparing Cardiovascular Events Across Home Dialysis Modalities: Adjusting the Unadjustable? Kidney360. 2024 Apr 1;5(4):489-491. doi: 10.34067/KID.0000000000000397. PMID: 38662536.