Transcriptional signatures differentiate pathogen- and treatment-specific host responses in patients with bacterial bloodstream infections

By sjmartinez • November 25, 2023

Thaden JT, Ahn R, Ruffin F, Gjertson DW, Hoffmann A, Fowler VG Jr, Yeaman MR. Transcriptional signatures differentiate pathogen- and treatment-specific host responses in patients with bacterial bloodstream infections. J Infect Dis. 2023 Nov 24:jiad498. doi: 10.1093/infdis/jiad498. Epub ahead of print. PMID: 38001039.

Tags: bacteremia, Escherichia coli, Infectious Diseases, Klebsiella pneumoniae, Molecular Medicine, Publications, Staphylococcus aureus, transcriptome

Efficacy assessments of SF001, a next-generation polyene antifungal, in a neutropenic mouse model of invasive fusariosis

Gebremariam T, Gu Y, Patterson H, Youssef E, Alkhazraji S, Elsayed T, Wiederhold NP, Ibrahim AS. Efficacy assessments of SF001, a next-generation polyene antifungal, in[...]

Clinical Telavancin Failure in Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia

Dao KT, D'Assumpcao C, Sharma R, Singh C, Kuran R, Heidari A. Clinical Telavancin Failure in Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia. Cureus. 2025 Feb 24;17(2):e79588.[...]

Implementation of a seamless phase 2/3 study design in the setting of an emergent infectious disease pandemic: Lessons learned from the ACTIV-2 platform COVID-19 treatment trial

Giganti MJ, Chew KW, Moser C, Eron JJ, Pinilla M, Li JZ, Ritz J, Javan AC, Wohl DA, Daar ES, Currier JS, Smith DM, Hughes[...]