Statistical Challenges When Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials

By sjmartinez • August 31, 2023

Moser CB, Chew KW, Giganti MJ, Li JZ, Aga E, Ritz J, Greninger AL, Javan AC, Bender Ignacio R, Daar ES, Wohl DA, Currier JS, Eron JJ, Smith DM, Hughes MD; ACTIV-2/A5401 Study Team. Statistical Challenges When Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials. J Infect Dis. 2023 Aug 31;228(Supplement_2):S101-S110. doi: 10.1093/infdis/jiad285. PMID: 37650235; PMCID: PMC10469328.

Tags: covid-19, Harbor UCLA, Infectious Diseases, linear regression for censored data, Publications, randomized trial, SARS-CoV-2 RNA

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