Lipophilic statins inhibit YAP coactivator transcriptional activity in HCC cells through Rho-mediated modulation of actin cytoskeleton

By sjmartinez • August 15, 2023

Benhammou JN, Qiao B, Ko A, Sinnett-Smith J, Pisegna JR, Rozengurt E. Lipophilic statins inhibit YAP coactivator transcriptional activity in HCC cells through Rho-mediated modulation of actin cytoskeleton. Am J Physiol Gastrointest Liver Physiol. 2023 Sep 1;325(3):G239-G250. doi: 10.1152/ajpgi.00089.2023. Epub 2023 Jun 27. PMID: 37366601.

Tags: chemoprevention, Digestive Diseases, Hepatocellular carcinoma, Publications, statin, Veterans Administration, YAP

The Legal and Ethical Framework for Artificial Intelligence in Gastrointestinal Endoscopy: A World Endoscopy Organization International Consensus Statement

Ahmad OF, Mori Y, Bretthauer M, Dourado DA, Hassan C, Bisschops R, Bhandari P, Byrne MF, Dekker E, Mahadevan U, May FP, Messmann H, Misawa[...]

Pain and IBD: The Contributing Role of Diet and Nutrition

Kuang R, Levinthal DJ, Cummings C, Ramos Rivers C, Ghaffari AA, Binion DG. Pain and IBD: The Contributing Role of Diet and Nutrition. Dig Dis[...]

Management of Refractory Hepatic Encephalopathy

Vongsavath T, Manne V, Sakae C, Saab S. Management of Refractory Hepatic Encephalopathy. Dig Dis Sci. 2025 Dec 5. doi: 10.1007/s10620-025-09591-x. Epub ahead of print.[...]