Efficient manufacturing and engraftment of CCR5gene-edited HSPCs following busulfan conditioning in nonhuman primates

By sjmartinez • August 14, 2023

Murray J, Einhaus T, Venkataraman R, Radtke S, Zhen A, Carrillo MA, Kitchen SG, Peterson CW, Kiem HP. Efficient manufacturing and engraftment of CCR5 gene-edited HSPCs following busulfan conditioning in nonhuman primates. Mol Ther Methods Clin Dev. 2023 Jul 18;30:276-287. doi: 10.1016/j.omtm.2023.07.006. PMID: 37575091; PMCID: PMC10415663.

Tags: autologous transplant, cell therapy, conditioning, CRISPR, Gene therapy, Hematology/Oncology, hematopoietic stem cells, nonhuman primate, Publications

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