Preclinical and clinical activity of DZD1516, a full blood-brain barrier-penetrant, highly selective HER2 inhibitor

By sjmartinez • July 7, 2023

Zhang J, McAndrew NP, Wang X, Du Y, DiCarlo B, Wang M, Chen K, Yu W, Hu X. Preclinical and clinical activity of DZD1516, a full blood-brain barrier-penetrant, highly selective HER2 inhibitor. Breast Cancer Res. 2023 Jul 6;25(1):81. doi: 10.1186/s13058-023-01679-4. PMID: 37415239.

Tags: blood–brain barrier, breast cancer, Central nervous system metastases, Hematology/Oncology, HER2, Publications, Tyrosine kinase inhibitor

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