Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring

By sjmartinez • July 4, 2023

Li S, Zeng W, Ni X, Liu Q, Li W, Stackpole ML, Zhou Y, Gower A, Krysan K, Ahuja P, Lu DS, Raman SS, Hsu W, Aberle DR, Magyar CE, French SW, Han SB, Garon EB, Agopian VG, Wong WH, Dubinett SM, Zhou XJ. Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2305236120. doi: 10.1073/pnas.2305236120. Epub 2023 Jul 3. PMID: 37399400.

Tags: cell-free DNA, Digestive Diseases, disease diagnosis, disease monitoring, DNA methylation, Hematology/Oncology, Publications, Pulmonary, Critical Care & Sleep Medicine, tissue deconvolution

Natural History of Indeterminate Liver Nodules in Patients With Advanced Liver Disease: A Multicenter Retrospective Cohort Study

Singal AG, Parikh ND, Shetty K, Han SH, Xie C, Ning J, Rinaudo JA, Arvind A, Lok AS, Kanwal F; Translational Liver Cancer Investigators. Natural[...]

HLA class I antibody-activated endothelium promotes CD206+ M2-macrophage polarization and MMP9 secretion through TLR4 signaling and P-selectin in a model of antibody-mediated rejection and allograft vasculopathy

Nevarez-Mejia J, Jin YP, Pickering H, Parmar R, Valenzuela NM, Sosa RA, Heidt S, Fishbein GA, Rozengurt E, William MB 3rd, Fairchild RL, Reed EF.[...]

Impact of phosphatidylethanol in the surveillance for alcohol use in post-liver transplant population: A retrospective study

De La Torre SA, Ibrahim B, Meneses K, Saab S, Shetty A. Impact of phosphatidylethanol in the surveillance for alcohol use in post-liver transplant population:[...]