Early and recent exposure to adversity, TLR-4 stimulated inflammation, and diurnal cortisol in women with interstitial cystitis/bladder pain syndrome: A MAPP research network study

By sjmartinez • June 12, 2023

Lutgendorf SK, Zia S, Luo Y, O'Donnell M, van Bokhoven A, Bradley CS, Gallup R, Pierce J, Taple BJ, Naliboff BD, Quentin Clemens J, Kreder KJ, Schrepf A. Early and recent exposure to adversity, TLR-4 stimulated inflammation, and diurnal cortisol in women with interstitial cystitis/bladder pain syndrome: A MAPP research network study. Brain Behav Immun. 2023 Jul;111:116-123. doi: 10.1016/j.bbi.2023.03.024. Epub 2023 Mar 29. PMID: 37001828.

Tags: Chronic stress, cortisol, Digestive Diseases, Early life adversity, HPA axis, IC/BPS, Inflammation, interstitial cystitis, pain, Publications, Recent life adversity

Genetic and pharmacologic modulations elucidate NRF2 protective role in acute pancreatitis

Mareninova OA, Chang AG, Hernandez Malpica S, Pineda JA, Mamita R, Shalbueva N, Gukovsky I, Gukovskaya AS. Genetic and pharmacologic modulations elucidate NRF2 protective role[...]

Plasma proteomics framework predicts metabolic dysfunction-associated steatotic liver disease up to 16 years before onset

Yu S, Chen C, Feng J, Li Q, Chen S, Zeng R, Luo D, Huang W, Zhang K, Ma Y, Zhang L, Meng M, Wu[...]

Closing the completion colonoscopy gap: key takeaways from the American Society for Gastrointestinal Endoscopy’s 2025 National Colorectal Cancer Screening Summit

Hosseini-Carroll P, Dominitz JA, Jacobson BC, May FP, Issaka RB, Schmitt CM, Adams TL, Boston IJ, Bucobo JC, Day L, Khaykis IB, Marino MJ, Rex[...]