Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD

By sjmartinez • May 26, 2023

Park SH, Helsley RN, Fadhul T, Willoughby JLS, Noetzli L, Tu HC, Solheim MH, Fujisaka S, Pan H, Dreyfuss JM, Bons J, Rose J, King CD, Schilling B, Lusis AJ, Pan C, Gupta M, Kulkarni RN, Fitzgerald K, Kern PA, Divanovic S, Kahn CR, Softic S. Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD. Metabolism. 2023 May 23:155591. doi: 10.1016/j.metabol.2023.155591. Epub ahead of print. PMID: 37230214.

Tags: Cardiology/Epi, ER stress, Fructose, Ketohexokinase, NAFLD, Publications, Sugar

Aspirin-Ticagrelor Use after Mild Acute Ischemic Stroke: Findings from the Get With The Guidelines-Stroke Registry

Liberman AL, Zhang C, Rostanski SK, Kamel H, Navi BB, Cheng NT, Sundararajan R, Messe SR, Fonarow GC, Prabhakaran S, Xian Y. Aspirin-Ticagrelor Use after[...]

Impact of Estrogen Replacement on Endothelial Dysfunction and Psychological Health in Women With Hypothalamic Amenorrhea

Shufelt CL, Safwan N, Saadedine M, Cook-Wiens G, Maughan J, Pisarska MD, Manson JE, Berga SL, Faubion SS, Shah PK, Merz CNB. Impact of Estrogen[...]

Association Between Single-Pill Combination Therapy Use and Blood Pressure Control in the Systolic Blood Pressure Reduction Intervention Trial (SPRINT): A Post-Hoc Analysis

Rao S, Segar MW, Keshvani N, Soni S, Agarwal A, Huffman M, Hsue P, Vongpatanasin W, Ramachandran V, Wang T, Pandey A. Association Between Single-Pill[...]