Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD

By sjmartinez • May 26, 2023

Park SH, Helsley RN, Fadhul T, Willoughby JLS, Noetzli L, Tu HC, Solheim MH, Fujisaka S, Pan H, Dreyfuss JM, Bons J, Rose J, King CD, Schilling B, Lusis AJ, Pan C, Gupta M, Kulkarni RN, Fitzgerald K, Kern PA, Divanovic S, Kahn CR, Softic S. Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD. Metabolism. 2023 May 23:155591. doi: 10.1016/j.metabol.2023.155591. Epub ahead of print. PMID: 37230214.

Tags: Cardiology/Epi, ER stress, Fructose, Ketohexokinase, NAFLD, Publications, Sugar

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